반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][N:12]([CH3:14])[C:11](=[N:15][C:16]#[N:17])[N:10]([CH3:18])[CH2:9]2)=[CH:4][C:3]=1[C:19]1[CH2:24][CH2:23][C:22]([CH3:26])([CH3:25])[CH2:21][CH:20]=1.[C:27]([C:29]1[N:30]=[C:31]([C:42](O)=[O:43])[N:32]([CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:41])([CH3:40])[CH3:39])[CH:33]=1)#[N:28].C1(C2C=C(C3CC(=O)NC(=O)C3)C=CC=2NC(C2NC=C(C#N)N=2)=O)CCCCC=1>>[C:16]([N:15]=[C:11]1[N:12]([CH3:14])[CH2:13][CH:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:42]([C:31]3[N:32]([CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:41])([CH3:40])[CH3:39])[CH:33]=[C:29]([C:27]#[N:28])[N:30]=3)=[O:43])=[C:3]([C:19]3[CH2:24][CH2:23][C:22]([CH3:26])([CH3:25])[CH2:21][CH:20]=3)[CH:4]=2)[CH2:9][N:10]1[CH3:18])#[N:17]참가 물질
4
반응물 3
생성물 1
실험 절차
5-[4-Amino-3-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-1,3-dimethyl-tetrahydro-pyrimidin-2-ylidene-cyanamide (as prepared in the previous step) was coupled to 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid, potassium salt (as prepared in Example 1) as described in Example 1, step (1) to obtain the title compound: Mass spectrum (ESI, m/z): Calcd. for C32H44N8O2Si, 601.3 (M+H). found 601.3.
출처 및 근거
- ORD 기록
- ord-afb3fdb2e45d4afe904976c375e28a70
- 출처 데이터셋
- uspto-grants-2014_11
- 특허 번호
- US08895584B2
연결된 노트
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