(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester → HCID 60035026, 화합물

HRID 34106노트

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HRID 34106 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][N:15]=[N+]=[N-])=[CH:12][CH:13]=1)([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][NH2:15])=[CH:12][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

참가 물질

4

반응물 1

HCID 60053847(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester

생성물 1

HCID 60035026HCID 60035026, 화합물수율 101.9%

시약·촉매·용매 2

HCID 131709914Lindlars catalyst촉매HCID 702Ethanol용매

실험 절차

To a solution of 88.6 mg of (5-azidomethyl-furan-2-ylmethyl)-carbamic acid tert-butyl ester in 3 mL of ethanol was added 30 mg of Lindlar catalyst, stirred at room temperature under hydrogen atmosphere for 15 hours, the catalyst filtered off, and the solvent was evaporated, to afford 81 mg of the title compound as a colorless oil.

후처리

  1. filtrationthe catalyst filtered off
  2. customthe solvent was evaporated

출처 및 근거

ORD 기록
ord-c1cd73bbdc5141dab72dbd3f5b96d8e6
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429609B2

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