Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → beta-Methyl-alpha-phenyl-1-pyrrolidineethanol hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | 1-Phenyl-2-(pyrrolidin-1-yl)propan-1-ol | HCID 4079506 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | beta-Methyl-alpha-phenyl-1-pyrrolidineethanol hydrochloride | HCID 53395958 | — |
반응 단계
adding a solution of hydrogen chloride in isopropanol to a toluene solution of [R-(R*,S*)]-β-methyl-α-phenyl-1-pyrrolidineethanol or its enantiomer at about 10° to about 15° C. and maintaining a reaction temperature of about 10° to about 25° C. to form [R-(R*,S*)]-β-methyl-α-phenyl-1-pyrrolidineethanol hydrochloride or its enantiomer;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05856492 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-291ec677f243435d9c65ff0f059cfb75 |
| 출처 메모 | uspto-grants-1999_01 |