참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | trans-1,4-Dibromo-2-butene | HCID 641245 | — |
| 반응물 | 4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazin-7-ol | HCID 135501633 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 7-(4-bromo-but-2-enyloxy)-4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazine | HCID 67684159 | 78.3% |
반응 단계
A mixture of 1.28 g of 4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazin-7-ol, 2.71 g of (E)-1,4-dibromo-2-butene and 1.74 g of potassium carbonate in 80 ml of acetone is stirred at 65° C. After cooling the reaction mixture is filtered and the filtrate is concentrated and purified by chromatography (silica gel, toluene/acetone 98:2). There are obtained 1.44 g of 7-(4-bromo-but-2-enyloxy)-4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazine, MS: m/e 437 (64%, M+, 2 Br).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05856503 |
|---|
| 출처 데이터셋 | uspto-grants-1999_01 |
|---|
| ORD ID | ord-a8dd78e614b643caa44ffaa4cc4cd5ae |
|---|
| 출처 메모 | uspto-grants-1999_01 |
|---|
