Peracetic Acid → Quinoline 1-oxide

HRID 34262

반응식

HRID 34262 반응식
C(OO)(=[O:3])C.[N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1>>[N+:6]1([O-:3])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1

참가 물질

3

반응물 2

HCID 6585Peracetic AcidHCID 7047Quinoline

생성물 1

HCID 15366Quinoline 1-oxide

실험 절차

Peracetic acid (7.5 mL, 39 mmole, 40%) and quinoline (5 g, 39 mmole) were stirred for 2 hours. Much of the acetic acid was removed from the reaction mixture in vacuo. The resulting residue was dissolved in methylene chloride (50 mL) and washed twice with saturated sodium bicarbonate solution. After drying over MgSO4 the solvent was evaporated and the residue was triturated with ether. The resulting tan solid was collected by filtration. This material was carried on without further characterization.

후처리

  1. customMuch of the acetic acid was removed from the reaction mixture in vacuo
  2. dissolutionThe resulting residue was dissolved in methylene chloride (50 mL)
  3. washwashed twice with saturated sodium bicarbonate solution
  4. dry with materialAfter drying over MgSO4 the solvent
  5. customwas evaporated
  6. customthe residue was triturated with ether
  7. filtrationThe resulting tan solid was collected by filtration

출처 및 근거

ORD 기록
ord-fbb987f1da9849cb93d557b6a2157e9e
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04761403

연결된 노트

불러오는 중…