Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-Methylsulfonylacetophenone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ethylenediaminetetraacetic Acid | HCID 6049 | — |
| 반응물 | 1-(4-Methyl-2-thienyl)ethan-1-one | HCID 83654 | — |
| 반응물 | Sodium Pyrosulfite | HCID 656671 | — |
| 반응물 | Potassium hydroxy sulfite | HCID 23707502 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-Methylsulfonylacetophenone | HCID 82529 | — |
반응 단계
A solution of 1036 g of oxone and 11.7 g of EDTA (Ethylene diamine tetraacetic acid) dissolved in 3.8 l of water is added dropwise to a solution of (4-methylthiophenyl)ethanone (prepared according to J. Am. Chem. Soc. 1952 p. 5475) in 1 l of acetone and 1.1 l of water, the temperature being kept below 32° C. The reaction mixture is stirred for 16 h after the end of the addition, then 550 g of sodium metabisulphite are added portionwise. The reaction mixture is then filtered, the solid obtained is taken up in water, dried in the oven and recrystallised from ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05859036 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-9d0b9ce9dd594b1b83638059fc6fe3bc |
| 출처 메모 | uspto-grants-1999_01 |