Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodoethane → HCID 12515028, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Tetramethylammonium Hydroxide Pentahydrate | HCID 82620 | — |
| 반응물 | BOC-D-alanine | HCID 637606 | — |
| 반응물 | N-(12-methoxy-1-oxododecyl)-D-alanine, ethyl ester | HCID 15870267 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | HCID 12515028 | HCID 12515028 | — |
반응 단계
Reaction Scheme 6 illustratively shows the preparation of N-(12-methoxy-1-oxododecyl)-D-alanine, ethyl ester wherein N-(t-butyloxycarbonyl)-D-alanine (16) is treated with tetramethylammonium hydroxide pentahydrate in acetonitrile followed by the addition of ethyl iodide to form N-(t-butyloxycarbonyl)-D-alanine, ethyl ester (17) which in turn reacts with trifluoroacetic acid in methylene chloride to give the trifluoroacetate salt of D-alanine ethyl ester (18) which, when treated with 2-methoxydodecanoyl chloride (9) in methylene chloride, gives the desired fatty acid amino ester (19).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05859052 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-c9943100722e477b81ddb31f495ec7d2 |
| 출처 메모 | uspto-grants-1999_01 |