Hydrogen Bromide → methyl N-(2-oxo-tetrahydrofur-3-yl)aminoacetate

참여 물질

역할	이름	HCID	투입량
반응물	Hydrogen Bromide	HCID 260	—
반응물	Homoserine Lactone	HCID 73509	—
반응물	Potassium Bromide	HCID 253877	—
용매	Chloroform	HCID 6212	—
생성물	methyl N-(2-oxo-tetrahydrofur-3-yl)aminoacetate	HCID 43825791	31%

반응 단계

This compound (9) was synthesized from (±)-α-amino-γ-butyrolactone×HBr using a method analogous to the synthesis described in Example 4. FC (silica gel, CHCl3). Yield: 31%. IR (KBr): 3333 (N--H), 1770, 1740 (C=O), 1216, 1165 (C--O). 1H-NMR (CDCl3): 2.05-2.18 (m, 1H); 2.47-2.57 (m, 1H); 3.57 (d, J=17.6, 1H); 3.63 (d, J=17.6, 1H); 3.64 (dd, J=8.1, 9.8, 1H); 3.75 (s, 3H); 4.21 (dt, J=6.3, 9.8, 1H); 4.42 (dt, J=2.3, 8.8, 1H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US05859215
출처 데이터셋	uspto-grants-1999_01
ORD ID	ord-c0136769771447789134f00649300e55
출처 메모	uspto-grants-1999_01