Ethanol → 2-(6-Methyl-1H-indol-3-yl)ethan-1-amine

HRID 343451노트

반응식

HRID 343451 반응식
[CH3:1][C:2]1[C:10](Br)=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C(O)C>C(N(CC)CC)C>[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 702EthanolHCID 15274383HCID 15274383, 화합물

생성물 1

HCID 1900062-(6-Methyl-1H-indol-3-yl)ethan-1-amine

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

A sample of 6-methyl-7-bromo-1 H-indole-3-ethanamine was contacted with Pd/C H2 in the presence of ethanol and triethylamine. The resulting material was evaporated and partitioned between base/CHCl3. The organic phase was dried, concentrated, and dried. The resulting material was taken up into methanol and added to ethereal HCl. The resulting material was washed and vacuum dried.

후처리

  1. customThe resulting material was evaporated
  2. custompartitioned between base/CHCl3
  3. customThe organic phase was dried
  4. concentrationconcentrated
  5. customdried
  6. additionadded to ethereal HCl
  7. washThe resulting material was washed
  8. customvacuum dried

출처 및 근거

ORD 기록
ord-63cb0fb11e5e404dbf2452123b65fdb4
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05861425

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