Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → N,N-Bis(2-chloroethyl)benzylamine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 2,2'-((Phenylmethyl)imino)bisethanol | HCID 7553 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | N,N-Bis(2-chloroethyl)benzylamine hydrochloride | HCID 2777881 | — |
반응 단계
Thionyl chloride (25.4 g, 130 mmol) and chloroform (20 mL) are combined. A solution of N,N-bis(2-hydroxyethyl)-N-benzylamine (25.4 g, 130 mmol) in chloroform (20 mL) is added dropwise over 1 hour. When the addition is complete the reaction mixture is refluxed for 1 hour. The reaction mixture is cooled to ambient temperature and diethyl ether was added to form a solid which is collected by filtration, rinsed with diethyl ether, and dried to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05861416 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-568798d80066492ebccf12203445f218 |
| 출처 메모 | uspto-grants-1999_01 |