5-(4-Cyano-2-vinylphenyl)hydantoin → 5-(4-Cyano-2-ethylphenyl)hydantoin

HRID 343946노트

반응식

HRID 343946 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([CH:16]=[CH2:17])[CH:4]=1)#[N:2]>CO.[C].[Pd]>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([CH2:16][CH3:17])[CH:4]=1)#[N:2]

참가 물질

4

반응물 1

HCID 700787825-(4-Cyano-2-vinylphenyl)hydantoin

생성물 1

HCID 700749315-(4-Cyano-2-ethylphenyl)hydantoin

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 887Methanol용매

실험 절차

A solution of 5-(4-cyano-2-vinylphenyl)hydantoin (75 mg, 0.35 mmol) in methanol (20 ml) was shaken with 10% palladium-carbon (10 mg) under an atmosphere of hydrogen for 0.5 hours at 25 p.s.i. The catalyst was removed by filtration to give 5-(4-cyano-2-ethylphenyl)hydantoin in a quantitative yield as a colourless oil.

후처리

  1. customThe catalyst was removed by filtration

출처 및 근거

ORD 기록
ord-608ac58e1aee4ed39d354c323246d5bc
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05863947

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