Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Chloride → Methyl 2-(4-benzyloxyphenyl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Chloride | HCID 7503 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Benzeneacetic acid, 4-hydroxy-, methyl ester | HCID 518900 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Methyl 2-(4-benzyloxyphenyl)acetate | HCID 2756645 | — |
반응 단계
Methyl 4-hydroxyphenylacetate (5, 0.2 mol), obtainable from Aldrich Chemical Co. Inc., Milwaukee, Wis., is heated at reflux with benzyl chloride (25 g, 0.2 mol) and K2CO3 (25 g, 0.2 mol) in 100 mL ethanol. The product is added to dilute aqueous NaOH, extracted with ether, and purified by silica gel chromatography to yield methyl 4-benzyloxyphenylacetate (6). (Scheme II, Step 1.)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04761420 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-9c76812738bd47cb8d4850477591476a |
| 출처 메모 | uspto-grants-1988_08 |