HCID 15069208, 화합물 → HCID 10250278, 화합물

반응식

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]C(C)(C)C)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([CH3:34])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].FC(F)(F)C(O)=O.C(Cl)Cl>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[CH:30]=[C:31]([CH3:34])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

참가 물질

반응물 2

HCID 15069208HCID 15069208, 화합물

HCID 21863450Trifluoroacetic acid methylene chloride

생성물 1

HCID 10250278HCID 10250278, 화합물

실험 절차

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-methyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid/methylene chloride.

출처 및 근거

ORD 기록: ord-f640374b0c8f491abbe4759bee75d32a
출처 데이터셋: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05864043

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