Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 4-Amino-N-(1-(3-aminopropyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 4-Amino-5-chloro-N-(1-(3-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)propyl)piperidin-4-ylmethyl)-2-methoxybenzamide | HCID 54150313 | — |
| 생성물 | 4-Amino-N-(1-(3-aminopropyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide | HCID 53895664 | 63.9% |
반응 단계
4-Amino-5-chloro-N-(1-(3-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)propyl)piperidin-4-ylmethyl)-2-methoxybenzamide (7.7 g) as starting compound and hydrazine monohydrate (0.76 ml) were reacted and treated in the same manner as in Example 117 to give 3.6 g of 4-amino-N-(1-(3-aminopropyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05864039 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-abbc4d0f3fae4a38972230af87441518 |
| 출처 메모 | uspto-grants-1999_01 |