Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromo-1-phenyl-1-butanone → 4-amino-5-chloro-2-methoxy-N-((1-(4-oxo-4-phenylbutyl)piperidin-4-yl)methyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromo-1-phenyl-1-butanone | HCID 90356 | — |
| 반응물 | 4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride | HCID 69966330 | — |
| 생성물 | 4-amino-5-chloro-2-methoxy-N-((1-(4-oxo-4-phenylbutyl)piperidin-4-yl)methyl)benzamide | HCID 54563895 | 37% |
반응 단계
4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (7 g) and 4-bromo-1-phenyl-1-butanone (4.93 g) were reacted and treated in the same manner as in Example 172 to give 3.1 g of 4-amino-5-chloro-2-methoxy-N-((1-(4-oxo-4-phenylbutyl)piperidin-4-yl)methyl)benzamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05864039 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-72def7c9b5314e758058ce1d2238c3ba |
| 출처 메모 | uspto-grants-1999_01 |