Hexahydro-1,4-diazepine → 2-(1,4-Diazepan-1-yl)-5-propylbenzenesulfonic acid

반응식

F[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH3:10])=[CH:4][C:3]=1[S:11]([OH:14])(=[O:13])=[O:12].[NH:15]1[CH2:21][CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1>>[N:15]1([C:2]2[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH3:10])=[CH:4][C:3]=2[S:11]([OH:14])(=[O:13])=[O:12])[CH2:21][CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1

참가 물질

반응물 2

HCID 68163Hexahydro-1,4-diazepine

HCID 14994783HCID 14994783, 화합물

생성물 1

HCID 98574372-(1,4-Diazepan-1-yl)-5-propylbenzenesulfonic acid수율 37.2%

실험 절차

According to the same method as in Example 2, from 0.61 g of 2-fluoro-5-n-propylbenzenesulfonic acid and 2.80 g of homopiperazine, 0.31 g (yield: 37.2%) of the above title product having the following physical property was obtained.

출처 및 근거

ORD 기록: ord-9de7aacdef4d42aea1e1fcaea3cac336
출처 데이터셋: uspto-grants-1991_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05053409

반응 노트

불러오는 중…