Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluenesulfonic acid → 4'-[(S)-2-methylbutoxycarbonyl]biphenyl-4-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | 4'-Hydroxy-4-biphenylcarboxylic acid | HCID 301556 | — |
| 반응물 | (S)-2-methyl-1-butanol | HCID 2723602 | — |
| 생성물 | 4'-[(S)-2-methylbutoxycarbonyl]biphenyl-4-ol | HCID 13907538 | 41% |
반응 단계
3.75 g of 4-hydroxybiphenyl-4'-carboxylic acid was heated under reflux together with (S)-2-methylbutyl alcohol in the presence of 0.10 g of p-toluenesulfonic acid for about 6 hours. Then the mixture was filtered to remove the unreacted 4-hydroxybiphenyl-4'-carboxylic acid. Next, the filtrate was evaporated and the unreacted (S)-2-methylbutyl alcohol was distilled off. The crystals thus obtained were recrystallized from 200 ml of n-hexane. Thus, 2.05 g of the corresponding colorless compound was obtained (Yield: 41%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05055225 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-cf17dec162e3440886c834555d7b68d0 |
| 출처 메모 | uspto-grants-1991_10 |