4-((Dimethylamino)methyl)benzonitrile → HCID 19993416, 화합물

HRID 344994노트

반응식

HRID 344994 반응식
[CH:1]1[C:18]2[C:5](=[C:6]([C:19]3[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=3)[CH2:22][Br:23])[C:7]3[C:16]([CH:17]=2)=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[CH3:27][N:28]([CH2:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]#[N:38])=[CH:33][CH:32]=1)[CH3:29].[PH4+].[AsH4+]>C(#N)C.C(OCC)C>[Br-:23].[C:37]([C:34]1[CH:33]=[CH:32][C:31]([CH2:30][N+:28]([CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[C:19]([C:6]3[C:7]4[C:16](=[CH:15][C:14]5[C:9]([CH:8]=4)=[CH:10][CH:11]=[CH:12][CH:13]=5)[CH:17]=[C:18]4[C:5]=3[CH:4]=[CH:3][CH:2]=[CH:1]4)[CH:20]=2)([CH3:27])[CH3:29])=[CH:36][CH:35]=1)#[N:38]

참가 물질

7

반응물 4

HCID 8263294-((Dimethylamino)methyl)benzonitrileHCID 5460504PhosphoniumHCID 5460506ArsoniumHCID 19993410HCID 19993410, 화합물

생성물 1

HCID 19993416HCID 19993416, 화합물

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 6342Acetonitrile용매

실험 절차

A mixture of (B) and N,N-dimethyl-4-cyanobenzylamine in acetonitrile was refluxed for 2 hr. The reaction mixture was then poured into diethyl ether, and the crude product was collected by filtration. The crude product was recrystallized from ethanol. The same reaction can be used to prepare the corresponding phosphonium and arsonium salts.

후처리

  1. temperaturewas refluxed for 2 hr
  2. filtrationthe crude product was collected by filtration
  3. customThe crude product was recrystallized from ethanol
  4. customThe same reaction

출처 및 근거

ORD 기록
ord-170f77478cd344a1a077d6f87d7c2d30
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05055376

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