2-Ethylimidazole → 1-Ethylimidazo[1,5-a]pyrido[4,5-e]pyrazine-4(5H)-one

HRID 345003

반응식

HRID 345003 반응식
F[C:2]1[CH:3]=[N+:4]([O-])[CH:5]=[CH:6][C:7]=1[N+:8]([O-])=O.[CH2:12]([C:14]1[NH:15][CH:16]=[CH:17][N:18]=1)[CH3:13].[C:19](N1C=CN=C1)(N1C=CN=C1)=[O:20]>[Pd]>[CH2:12]([C:14]1[N:18]2[C:2]3[CH:3]=[N:4][CH:5]=[CH:6][C:7]=3[NH:8][C:19](=[O:20])[C:17]2=[CH:16][N:15]=1)[CH3:13]

참가 물질

5

반응물 3

HCID 661302-EthylimidazoleHCID 682631,1'-CarbonyldiimidazoleHCID 5940283-Fluoro-4-nitropyridin-1-ium-1-olate

생성물 1

HCID 198093911-Ethylimidazo[1,5-a]pyrido[4,5-e]pyrazine-4(5H)-one

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

Prepare by reaction of 3-fluoro-4-nitropyridine-N-oxide with 2-ethylimidazole followed by hydrogenation with Pd-C and cyclization with carbonyldiimidazole to provide the title compound.

출처 및 근거

ORD 기록
ord-3019ee0a71b7480b98c01ab0d7cd8498
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05055465

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