9,10-Dihydro-9,10-ethanoanthracene-11-methanol → 11-Bromomethyl-9,10-dihydro-9,10-ethanoanthracene

HRID 345018

반응식

HRID 345018 반응식
[CH:1]1[C:14]2[CH:13]3[CH2:15][CH:16]([CH2:17]O)[CH:6]([C:7]4[C:12]3=[CH:11][CH:10]=[CH:9][CH:8]=4)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Br-:19].[Br-].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:19][CH2:17][CH:16]1[CH:6]2[C:5]3[CH:4]=[CH:3][CH:2]=[CH:1][C:14]=3[CH:13]([C:12]3[C:7]2=[CH:8][CH:9]=[CH:10][CH:11]=3)[CH2:15]1

참가 물질

4

반응물 2

HCID 2443799,10-Dihydro-9,10-ethanoanthracene-11-methanolHCID 12890784Triphenylphosphane dibromide

생성물 1

HCID 352223811-Bromomethyl-9,10-dihydro-9,10-ethanoanthracene

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

9,10-Dihydro-9,10-ethanoanthracene-11-methanol (2 gm) was combined with triphenylphosphine dibromide (5.3 gm) in carbon tetrachloride (60 ml). The mixture was heated to reflux 1 hour, filtered, and the filtrate was concentrated on a rotary evaporator. The residue was boiled in n-heptane (75 ml), filtered hot, and the filtrate cooled. The white precipitate was filtered and air dried to provide the product (mp=103-106° C.).

후처리

  1. temperatureThe mixture was heated
  2. temperatureto reflux 1 hour
  3. filtrationfiltered
  4. concentrationthe filtrate was concentrated on a rotary evaporator
  5. filtrationfiltered hot
  6. temperaturethe filtrate cooled
  7. filtrationThe white precipitate was filtered
  8. customair dried

출처 및 근거

ORD 기록
ord-4d7034bb0008421d9dc6c0a2fc8c4057
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05055468

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