Ammonia → Naphthalenesulfonamide
반응식
[NH3:1].[C:2]1([S:12](Cl)(=[O:14])=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][CH:3]=1>CCOCC>[C:2]1([S:12]([NH2:1])(=[O:14])=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][CH:3]=1참가 물질
4
실험 절차
Ammonia was passed (for 5 min) into a stirred solution of 1-naphthalenesulfonyl chloride (5.0 g, 22 mmol) and anhydrous Et2O (400 ml) at -78°. The resulting mixture was stirred at -78° for 1 hr, allowed to warm to room temperature, and stirred overnight. The Et2O was removed under vacuum to leave a white powder which was washed with water and dried under vacuum to give 3.2 g (70%) of the title compound as a white powder, m.p. 152°-153° C.
후처리
- custom(for 5 min)
- customat -78°
- stirringstirred overnight
- customThe Et2O was removed under vacuum
- customto leave a white powder which
- washwas washed with water
- customdried under vacuum
출처 및 근거
- ORD 기록
- ord-7e4b5ab5aa724026b7222ee264a74f9c
- 출처 데이터셋
- uspto-grants-1991_10
- 특허 번호
- US05055450
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