Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 34534생성일: 2026년 10월 24일
2-Propynoic acid, 3-phenyl-, ethyl ester → ethyl 2-oxo-4-phenyl-2H-pyrimido[2,1-b]benzothiazole-8-acetate
https://huagongshe.com/ko/reaction/34534
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Propynoic acid, 3-phenyl-, ethyl ester | HCID 91516 | — |
| 반응물 | (2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester | HCID 821202 | — |
| 생성물 | ethyl 2-oxo-4-phenyl-2H-pyrimido[2,1-b]benzothiazole-8-acetate | HCID 13477943 | 26% |
반응 단계
A stirred mixture of 5 g of ethyl 2-aminobenzothiazole-6-acetate and 6 g of ethyl phenylpropiolate was heated at 200° C. in an oil bath for 1 hour and the crude mixture was then purified on a column of 200 g of silica using CHCl3 as eluant. The product obtained was highly colored and was crystallized from CHCl3 and crystallized from ethanol to obtain 1.99 g (26% yield) of ethyl 2-oxo-4-phenyl-2H-pyrimido[2,1-b]benzothiazole-8-acetate as orange plates.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US04762840 |
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| 출처 데이터셋 | uspto-grants-1988_08 |
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| ORD ID | ord-f4eb3194b1364147abc2863c106177f3 |
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| 출처 메모 | uspto-grants-1988_08 |
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