Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methylcyclohexyl 2-(p-nitrophenyl)propionate → 1-Methylcyclohexyl 2-(p-aminophenyl)-propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methylcyclohexyl 2-(p-nitrophenyl)propionate | HCID 54068492 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-Methylcyclohexyl 2-(p-aminophenyl)-propionate | HCID 13754071 | 67.1% |
반응 단계
A stirred solution of 34.9 g of 1-methylcyclohexyl 2-(p-nitrophenyl)-propionate in 250 ml of absolute ethanol was hydrogenated at atmospheric pressure in the presence of 10% palladium on carbon catalyst. After the uptake of hydrogen gas was complete, the catalyst was filtered off through celite and the filtrate was evaporated to dryness. Trituration of the residue with petroleum ether gave 21.02 g (67% yield) of 1-methylcyclohexyl 2-(p-aminophenyl)-propionate as creamy white crystals melting at 85°-87° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04762840 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-15fc9e5b04644708b922aada49328d83 |
| 출처 메모 | uspto-grants-1988_08 |