Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Bromide → 1-Phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | 1-Phenyl-3,4-dihydroisoquinoline | HCID 609926 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 1-Phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide | HCID 10809638 | — |
반응 단계
The mixture of 1-phenyl-3,4-dihydroisoquinoline (292.0 g) and benzyl bromide (176 ml) in acetonitrile (3 l) was refluxed for 1 hour. After cooling the mixture to room temperature, the solvent was evaporated in vacuo. The residue was triturated with diethyl ether (1 l) to give 1-phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide (471.2 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05059608 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-d03d24d666134bcbb7e9887a3efdf6d4 |
| 출처 메모 | uspto-grants-1991_10 |