Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-Formylbenzoate → 3-(4-Carbomethoxyphenyl)-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-prop-2-en-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-Formylbenzoate | HCID 15294 | — |
| 반응물 | 1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one | HCID 2747562 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 3-(4-Carbomethoxyphenyl)-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-prop-2-en-1-one | HCID 54221169 | 58.4% |
반응 단계
138 g (0.6 mole) of 6-acetyl-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene and 98.5 g (0.6 mole) of methyl 4-formylbenzoate in a mixture of 16 g of sodium hydroxide and 690 ml of methanol were stirred for 16 hours at room temperature. The precipitated crystals were filtered off under suction and dried to give 132 g of 3-(4-carbomethoxyphenyl)-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-prop-2-en-1-one of melting point 89°-91° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05061705 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-dfcc00fa2adc4dc1ad87edb6f478853e |
| 출처 메모 | uspto-grants-1991_10 |