Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → Methyl 4-carbamothioylbenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Methyl 4-cyanobenzoate | HCID 70791 | — |
| 반응물 | HCID 178418634 | HCID 178418634 | — |
| 용매 | Propan-2-ol--water (1/1) | HCID 21889133 | — |
| 생성물 | Methyl 4-carbamothioylbenzoate | HCID 11401319 | 77.7% |
반응 단계
130 g (1.7 moles) of thioacetic acid, 50 g (0.3 mole) of methyl 4-cyanobenzoate and 12 ml of glacial acetic acid were stirred for 2 hours at 80° C. The mixture was allowed to cool, 200 ml of 1:1 isopropanol/water was added, the mixture was stirred for a short time and the crystals formed were filtered off under suction. 45.5 g of 4-carbomethoxybenzothiamide of melting point 188°-190° C. were obtained in this manner.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05061705 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-981319bd557c4bf2a449627f74850574 |
| 출처 메모 | uspto-grants-1991_10 |