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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 346416생성일: 2026년 10월 26일

4,5-Dichloro-2-fluoroaniline → 4-[(3,4-Dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline

https://huagongshe.com/reaction/346416

반응식

참여 물질

역할이름HCID투입량
반응물4,5-Dichloro-2-fluoroanilineHCID 223091—
반응물4-Chloro-7-fluoro-6-nitroquinazolineHCID 10609358—
용매IsopropanolHCID 3776—
생성물4-[(3,4-Dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazolineHCID 1117618578%

반응 단계

3,4-Dichloro-6-fluoroaniline (1 equivalent) was reacted with 4-chloro-7-fluoro-6-nitroquinazoline (3.5 equivalents), in iso-propylalcohol. After filtration, 4-[(3,4-dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline was obtained in 78% yield.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07172749B2
출처 데이터셋uspto-grants-2007_02
ORD IDord-1042ad855505453485b72441af00c3ae
출처 메모uspto-grants-2007_02