Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzaldehyde → 1-p-Fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-(4-methylbenzylidene)amino-1-pyrrolidinyl)-quinoline-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | Pyrrole-2-carboxaldehyde | HCID 13854 | — |
| 반응물 | 1-p-Fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-amino-1-pyrrolidinyl)-quinoline-3-carboxylic acid | HCID 13500657 | — |
| 생성물 | 1-p-Fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-(4-methylbenzylidene)amino-1-pyrrolidinyl)-quinoline-3-carboxylic acid | HCID 14230012 | — |
반응 단계
In the described fashion of Example 1 replacing benzaldehyde with with 2-pyrrolecarboxaldehyde and using the acid (1) (R=cyclopropyl) described in Example 19 one can obtain 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-(2-pyrrylidene)amino-1-pyrrolidinyl)-quinoline-3-carboxylic acid (3) (R=cyclopropyl, Z=2-pyrrole).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04762845 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-c8c9b6e13349460dbfe48136a8f7c85d |
| 출처 메모 | uspto-grants-1988_08 |