Nitric Acid → 6-hydroxy-7-nitro-2H-1,4-benzoxazin-3-(4H)-one

HRID 34699노트

반응식

HRID 34699 반응식
[N+:1]([O-:4])(O)=[O:2].[OH:5][C:6]1[CH:7]=[CH:8][C:9]2[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=2[CH:16]=1>C(O)(=O)C>[OH:5][C:6]1[C:7]([N+:1]([O-:4])=[O:2])=[CH:8][C:9]2[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=2[CH:16]=1

참가 물질

4

반응물 2

HCID 944Nitric AcidHCID 113786896-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

생성물 1

HCID 212986856-hydroxy-7-nitro-2H-1,4-benzoxazin-3-(4H)-one

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

실험 절차

Fumic nitric acid (δ 1.52, 2.6 ml, 0.062 mole) in acetic acid (5 ml) was added dropwise under stirring to 6-hydroxy-2H-1,4-benzoxazin-3-(4H)-one (Coupler (1), 10.3 g, 0.062 mole) in acetic acid (100 ml) at room temperature. The 6-hydroxy-7-nitro-1,4-benzoxazin-3-one (6.7 g, 51%) separated as yellow prisms.

후처리

  1. customThe 6-hydroxy-7-nitro-1,4-benzoxazin-3-one (6.7 g, 51%) separated as yellow prisms

출처 및 근거

ORD 기록
ord-d29846ee8c384435adf5c7c1588d6c1e
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04762925

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