Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Trifluoromethyl)phenyl isocyanate → 4-[alpha-(2,4-Ditert.-pentylphenoxy)-butyroyl]-6-hydroxy-7-(4-trifluoromethylphenylureido)-1,4-benzoxazine-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Trifluoromethyl)phenyl isocyanate | HCID 73768 | — |
| 반응물 | 4-[alpha-(2,4-Ditert.-pentylphenoxy)-butyroyl]6-hydroxy-7-amino-1,4-benzoxazine-3-one | HCID 21298675 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-[alpha-(2,4-Ditert.-pentylphenoxy)-butyroyl]-6-hydroxy-7-(4-trifluoromethylphenylureido)-1,4-benzoxazine-3-one | HCID 86740820 | — |
반응 단계
4-Trifluoromethylphenylisocyanate (2.55 g, 0.0136 mole) was added to the amine ((g), 6.56 g, 0.0136 mole) in THF (ml 100). After 1 hour stirring, the solution was evaporated to dryness and the residue crystallized from toluene to give the coupler ((h), 6 g, 67%) as white prisms. The product structure was confirmed by NMR analysis.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04762925 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-bdd15068de3742a7b850ca63c0514cab |
| 출처 메모 | uspto-grants-1988_08 |