1,3-Dibromopropane → 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene

HRID 347163노트

반응식

HRID 347163 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]3[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][C:10]=3[S:11][CH:12]=2)=[CH:4][CH:3]=1.[Br:18][CH2:19][CH2:20][CH2:21]Br>>[Br:18][CH2:19][CH2:20][CH2:21][O:17][C:14]1[CH:15]=[CH:16][C:9]2[C:8]([C:5]3[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=3)=[CH:12][S:11][C:10]=2[CH:13]=1

참가 물질

3

반응물 2

HCID 80011,3-DibromopropaneHCID 223141963-(4-Fluoro-phenyl)-benzo[b]thiophen-6-ol

생성물 1

HCID 223140346-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene

실험 절차

In analogy to example 27.1, 3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-ol and 1,3-dibromopropane were converted to yield 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene, MS: 364 (M, 1Br).

출처 및 근거

ORD 기록
ord-7ff83102262f48b2a12e8d4d2a792d31
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07173043B2

반응 노트

불러오는 중…