Hexane → 2-(3-Hydroxyphenyl)-2-oxoacetaldehyde

반응식

CCCCCC.[CH3:7][C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[C:14]([OH:16])[CH:15]=1)=[O:9].C(OCC)(=[O:19])C>>[OH:16][C:14]1[CH:15]=[C:10]([C:8]([CH:7]=[O:19])=[O:9])[CH:11]=[CH:12][CH:13]=1

참가 물질

반응물 3

HCID 8058Hexane

HCID 84873-Hydroxyacetophenone

HCID 8857Ethyl Acetate

생성물 1

HCID 129108752-(3-Hydroxyphenyl)-2-oxoacetaldehyde

실험 절차

Using 1:1 hexane:ethyl acetate as eluant, the method of Preparation 68 was employed to convert 3-hydroxyacetophenone (15.0 g., 0.11 mol) to present title product, 7.4 g.; 1H-nmr (DMSO-d6) 7.09 (m, 2H), 7.43 (m, 3H), 9.75 (br m, 1H).

출처 및 근거

ORD 기록: ord-9c67623f0b554c5ea47564486370e681
출처 데이터셋: uspto-grants-1988_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04762921

반응 노트

불러오는 중…