Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1,1-Trifluoro-2-isothiocyanatoethane → HCID 178485065, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1,1-Trifluoro-2-isothiocyanatoethane | HCID 13883777 | — |
| 반응물 | HCID 178485066 | HCID 178485066 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 178485065 | HCID 178485065 | — |
반응 단계
A mixture of 2,2,2-trifluoroethyl isothiocyanate (0.68 g.) and 2-amino-4-[2-(2-cyano-3-methylguanidino)ethylthiomethyl]thiazole (1.08 g.) in dimethylformamide (5 ml.) was maintained at 60° for 4 hours and then evaporated to dryness. The residue was recrystallised from acetonitrile to give 2-[3-(2,2,2-trifluoroethyl)thioureido]-4-[2-(2-cyano-3-methylguanidino)ethylthiomethyl]thiazole, m.p. 157°-158°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04762932 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-5372c98e3cfb479abc30ca7e91934a83 |
| 출처 메모 | uspto-grants-1988_08 |