Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl (2-chlorophenyl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | o-Chlorophenylacetic acid | HCID 17124 | — |
| 촉매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | Methyl (2-chlorophenyl)acetate | HCID 93683 | 97.5% |
반응 단계
To 2-chlorophenylacetic acid (1.04 g, 6 mmol) in MeOH (25 mL) was added sulfuric acid (6 drops) and the solution was refluxed for 16 hours. After concentration, the residue was taken up in ethyl acetate and washed with sat'd aq. NaHCO3, H2O and brine. The organic layer was dried over Na2SO4 and concentrated to give methyl (2-chlorophenyl)acetate 6a (1.08 g, 97.5% ) as a yellowish oil. GCMS (EI) m/z 184, 186 (M+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07176211B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-3743fead2e244e8f877581d62ad96443 |
| 출처 메모 | uspto-grants-2007_02 |