3-Pyridineacetonitrile → 6-Pyridin-3-yl-pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 3478

반응식

HRID 3478 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]#[N:9])[CH:2]=1.[NH2:10][C:11]1[N:16]=[C:15]([NH2:17])[C:14]([CH:18]=O)=[CH:13][N:12]=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[C:8]([NH2:9])=[N:17][C:15]3[N:16]=[C:11]([NH2:10])[N:12]=[CH:13][C:14]=3[CH:18]=2)[CH:2]=1

참가 물질

3

반응물 2

HCID 809233-PyridineacetonitrileHCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

생성물 1

HCID 218500626-Pyridin-3-yl-pyrido[2,3-d]pyrimidine-2,7-diamine

실험 절차

The procedure of Example 1 was followed to react 3-pyridylacetonitrile and 2,4-diamino-5-pyrimidine-carboxaldehyde to afford the title compound; mp 317°-319° C. (dec).

출처 및 근거

ORD 기록
ord-4a76dcd362764370a4ab0d70f23633f8
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05733913

연결된 노트

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