4-(Pyridin-4-yloxy)benzene-1-sulfonyl chloride hydrochloride → HCID 21084204, 화합물

반응식

[C@@H:1]12[CH2:7][C@@H:4]([CH2:5][CH2:6]1)[C@H:3]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[NH:2]2.Cl.[N:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]2[CH:26]=[CH:25][C:24]([S:27](Cl)(=[O:29])=[O:28])=[CH:23][CH:22]=2)=[CH:16][CH:15]=1>>[N:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]2[CH:22]=[CH:23][C:24]([S:27]([N:2]3[CH:3]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH:4]4[CH2:7][CH:1]3[CH2:6][CH2:5]4)(=[O:29])=[O:28])=[CH:25][CH:26]=2)=[CH:16][CH:15]=1

참가 물질

반응물 2

HCID 27352574-(Pyridin-4-yloxy)benzene-1-sulfonyl chloride hydrochloride

HCID 10535139HCID 10535139, 화합물

생성물 1

HCID 21084204HCID 21084204, 화합물

실험 절차

Ethyl 2-azabicyclo[2.2.1]heptane-3-carboxylate obtained in Example 1 (b) is subjected to a reaction similar to the reaction (c) of Example 1 using [4-(4-pyridyloxy)phenyl]sulfonyl chloride hydrochloride in place of 4-methoxybenzenesulfonyl chloride, to give ethyl 2-{[4-(4-pyridyloxy)phenyl]sulfonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylate.

출처 및 근거

ORD 기록: ord-1d3aa72125774a41aa5b583de1fb04d5
출처 데이터셋: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07176217B2

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