Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → Oxane-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2H-Pyran-4-carboxylic acid, tetrahydro-, methyl ester | HCID 2773520 | — |
| 생성물 | Oxane-4-carboxamide | HCID 13197203 | 74.6% |
반응 단계
Concentrated aqueous ammonia (50 mL) was added to methyl tetrahydro-2H-pyran-4-carboxylate (50 g, 347 mmol) and the reaction mixture was stirred for 43.5 hours at room temperature. The reaction mixture was then cooled in an ice water bath, after which the precipitate was filtered out and dried under reduced pressure at 40° C. to afford 33.4 g of the title compound (74.6% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07176216B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-252e002dbf1d499fbd2f04606d198237 |
| 출처 메모 | uspto-grants-2007_02 |