Dabco → 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide

참여 물질

역할	이름	HCID	투입량
반응물	Dabco	HCID 9237	—
반응물	1-[4-(4-Bromomethylbenzyloxy)-phenyl]-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-(4-methoxyphenyl)-azetidin-2-one	HCID 21083167	—
용매	Toluene	HCID 1140	—
생성물	1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide	HCID 21083163	—

반응 단계

Compound (25) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (26) as a colorless solid of molecular weight 716.70 (C39H43BrFN3O4); MS (ESI): 636.3 (MH+).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07176194B2
출처 데이터셋	uspto-grants-2007_02
ORD ID	ord-d4c0ada96e6742f8ba6d87ca5a527f4b
출처 메모	uspto-grants-2007_02