Pyridine-2-acetonitrile → 6-Pyridin-2-yl-pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 3482

반응식

HRID 3482 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8]#[N:9].[NH2:10][C:11]1[N:16]=[C:15]([NH2:17])[C:14]([CH:18]=O)=[CH:13][N:12]=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[C:8]([NH2:9])=[N:17][C:15]2[N:16]=[C:11]([NH2:10])[N:12]=[CH:13][C:14]=2[CH:18]=1

참가 물질

3

반응물 2

HCID 75959Pyridine-2-acetonitrileHCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

생성물 1

HCID 218500586-Pyridin-2-yl-pyrido[2,3-d]pyrimidine-2,7-diamine

실험 절차

The procedure of Example 1 was followed to react 0.84 mL of 2-pyridylacetonitrile and 1.0 g of 2,4-diamino-5-pyrimidinecarboxaldehyde to afford the title compound, mp 312°-321° C.

출처 및 근거

ORD 기록
ord-1d437903b7d7465cbd657fadc7a517dd
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05733913

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