Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,3-Dimethyl-1-butanol → [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid 3,3-dimethyl-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,3-Dimethyl-1-butanol | HCID 12233 | — |
| 반응물 | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| 생성물 | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid 3,3-dimethyl-butyl ester | HCID 69523345 | 85% |
반응 단계
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 3,3-dimethylbutanol (26 mg, 0.26 mmol) as the coupling partner. Concentration (no chromatography) yielded 54 mg (85%) of the titled compound. ESI-MS m/z 376 (MH+), 374 (M−H−).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07176310B1 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-e17d57388c55403aa2bed5fa9b19099d |
| 출처 메모 | uspto-grants-2007_02 |