Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetate → HCID 86760394, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 3-Amino-N-butylbenzenesulfonamide | HCID 5137973 | — |
| 반응물 | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 86760394 | HCID 86760394 | 27% |
반응 단계
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 3-amino-N-butyl-benzenesulfonamide (53 mg, 0.21 mmol) as the coupling partner. Chromatography (1:1 ethyl acetate:dichloromethane) through SiO2 yielded 23 mg (27%) of the titled compound. ESI-MS m/z 502 (MH+), 500 (M−H−).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07176310B1 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-c61610a7835242e8bdb1272920cfc583 |
| 출처 메모 | uspto-grants-2007_02 |