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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 348750생성일: 2026년 10월 25일

2-Phthalimidomethyl-6-(4-dipropylaminobutyl)naphthalene → 2-Aminomethyl-6-(4-dipropylaminobutyl)naphthalene

https://huagongshe.com/reaction/348750

반응식

참여 물질

역할이름HCID투입량
반응물2-Phthalimidomethyl-6-(4-dipropylaminobutyl)naphthaleneHCID 21084392—
용매Monomethylamine methanolHCID 57454252—
생성물2-Aminomethyl-6-(4-dipropylaminobutyl)naphthaleneHCID 21084390127.5%

반응 단계

The compound (75.0 mg) obtained in Example 124-3 was dissolved in a 40% methylamine/methanol solution (2.0 ml) and stirred overnight at room temperature. After completion of the reaction, the solvent was distilled off and then the residue was added with a 1 mol/l sodium hydroxide aqueous solution and stirred. The solution was subjected to extraction with chloroform and the extract was then washed with saturated saline solution. Subsequently, the organic layer was dried with anhydrous sodium sulfate and the solvent was then distilled off, thereby obtaining the subject compound (67.5 mg) as a colorless oily substance.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07176227B2
출처 데이터셋uspto-grants-2007_02
ORD IDord-06f285c9b51643fe93d59be419362a9b
출처 메모uspto-grants-2007_02