Imiquimod → 4-(Acetylamino)benzoic acid-1-(dimethylamino)-2-propanol

HRID 348782

반응식

HRID 348782 반응식
[CH3:1][CH:2]([CH2:4][N:5]1[C:9]2C3C=CC=CC=3N=C(N)C=2N=[CH:6]1)C.C[C@@H](O)CCCC[N:25]1C(=O)N(C)C2N=CN(C)[C:28]=2[C:26]1=[O:27].C[C:40]1[C:45](OC)=[C:44](C/C=C(/CCC(OCCN2CCOCC2)=O)\C)[C:43](O)=[C:42]2[C:66]([O:68]C[C:41]=12)=[O:67]>CC(O)=O.C1N=CNC=1C[C@H](NC(CN)=O)C(N[C@H](C(O)=O)CCCCN)=O.[Cu+2]>[CH3:1][CH:2]([OH:27])[CH2:4][N:5]([CH3:9])[CH3:6].[CH3:28][C:26]([NH:25][C:45]1[CH:40]=[CH:41][C:42]([C:66]([OH:68])=[O:67])=[CH:43][CH:44]=1)=[O:27]

참가 물질

5

반응물 3

HCID 57469ImiquimodHCID 501254LisofyllineHCID 5281078Mycophenolate Mofetil

생성물 1

HCID 1621794-(Acetylamino)benzoic acid-1-(dimethylamino)-2-propanol

시약·촉매·용매 1

HCID 3086626copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid촉매

실험 절차

imiquimod; interferon beta-lb; lisofylline; mycophenolate mofetil; prezatide copper acetate.

출처 및 근거

ORD 기록
ord-97937031b38a4ab49b0cd63bd0d32b48
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07175854B2

연결된 노트

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