참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Iodine chloride | HCID 24640 | — |
| 반응물 | Benzoic acid, 4-hydroxy-3-nitro-, methyl ester | HCID 66835 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Methyl 4-hydroxy-3-iodo-5-nitrobenzoate | HCID 21086206 | 91,075.398% |
반응 단계
To a solution of methyl 4-hydroxy-3-nitrobenzoate (2.0 g) in acetic acid (15 mL) was added iodine monochloride (1.65 mg) in acetic acid, and the mixture was stirred at 100° C. for 1.5 h. After cooling to room temperature, the mixture was poured into water (200 mL), and stirred for 30 min. The mixture was filtered and washed with water and hexanes. The yellow powder was collected by filtration and dried in vacuum oven overnight to give 2.99 g of the title compound: 1H NMR (300 MHz, CDCl3) δ 11.68, 8.81, 8.72, 3.96.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07176242B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_02 |
|---|
| ORD ID | ord-ce3a917d547b4565ad207f5df577f15f |
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| 출처 메모 | uspto-grants-2007_02 |
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