Carbon Dioxide → Neopeltolide

HRID 349602

반응식

HRID 349602 반응식
CCN([CH2:6][CH2:7][O:8][C:9]([C:11]1[CH:16]=[CH:15][C:14](N)=[CH:13][CH:12]=1)=[O:10])CC.CC1(C)S[C@@H]2[C@H](NC([CH2:30][C:31]3[CH:36]=C[CH:34]=[CH:33][CH:32]=3)=O)C(=O)N2[C@H]1C(O)=O.[OH2:41].[NH2:42][C@H:43](C(O)=O)[CH2:44][CH2:45][C:46](=[O:48])[NH2:47].C1N(C[CH2:59][OH:60])CCN(CCS(O)(=O)=O)C1.CC(NC)C1O[CH:73]([O:75][CH:76]2[CH:81](O)[CH:80]([O:83][CH:84]3[O:89]CC(O)(C)[CH:86](NC)[CH:85]3O)[CH:79](N)[CH2:78][CH:77]2N)C(N)CC1.[C:100](=O)=[O:101]>>[CH3:77][CH2:78][CH2:79][C@H:80]1[O:83][C:84](=[O:89])[CH2:85][C@@H:86]2[O:41][C@@H:33]([CH2:34][C@@H:7]([O:8][C:9](/[CH:11]=[CH:16]\[CH2:15][CH2:14][C:13]3[N:47]=[C:46](/[CH:45]=[CH:44]\[CH2:43][NH:42][C:100]([O:60][CH3:59])=[O:101])[O:48][CH:12]=3)=[O:10])[CH2:6]2)[CH2:32][C@@H:31]([CH3:30])[CH2:36][C@@H:76]([O:75][CH3:73])[CH2:81]1

참가 물질

6

반응물 5

HCID 280Carbon DioxideHCID 3467GentamicinHCID 5961L-GlutamineHCID 225024-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-(2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate, hydrate (1:1:1)HCID 238314-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

생성물 1

HCID 16115403Neopeltolide

실험 절차

All cell lines are maintained in Roswell Park Memorial Institute (RPMI) medium 1640 supplemented with 100 U/mL penicillin 100 μg/ml streptomycin, 60 μg/ml L-glutamine, 18 mM HEPES, 0.05 mg/mL gentamycin and 10% fetal bovine serum. Cell lines are cultured in plastic tissue culture flasks and kept in an incubator at 37° C. in humidified air containing 5% CO2.

후처리

  1. temperatureAll cell lines are maintained in Roswell Park Memorial Institute (RPMI) medium 1640
  2. customCell lines are cultured in plastic tissue culture flasks
  3. customkept in an incubator at 37° C. in humidified air

출처 및 근거

ORD 기록
ord-54430c6430da44529262d57f7ce4b87f
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07179828B2

연결된 노트

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