Potassium Iodide → 2-Allyl-3,4-dichlorophenol

HRID 34966

반응식

HRID 34966 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:10](Br)[CH:11]=[CH2:12].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>C(C(C)=O)C>[CH2:12]([C:3]1[C:2]([Cl:1])=[C:7]([Cl:8])[CH:6]=[CH:5][C:4]=1[OH:9])[CH:11]=[CH2:10]

참가 물질

6

반응물 4

HCID 4875Potassium IodideHCID 72583,4-DichlorophenolHCID 7841Allyl bromideHCID 11430Potassium Carbonate

생성물 1

HCID 142330452-Allyl-3,4-dichlorophenol

시약·촉매·용매 1

HCID 6569Methyl Ethyl Ketone용매

반응 조건

온도
200 °C

실험 절차

A solution of 100 g. of 3,4-dichlorophenol, 50 ml. of allyl bromide, 84 g. of potassium carbonate, and 1.0 g. of potassium iodide in 500 ml. of methyl ethyl ketone was allowed to reflux overnight. The solution was then cooled, filtered, and evaporated to dryness. The residue was then heated at 200° C. for approximately four hours. NMR analysis indicated that the 113.6 g. of remaining material was primarily the desired 2-allyl-3,4-dichlorophenol.

후처리

  1. temperatureto reflux overnight
  2. temperatureThe solution was then cooled
  3. filtrationfiltered
  4. customevaporated to dryness

출처 및 근거

ORD 기록
ord-99355c9dac3a4ade8fb9d00ba4a791bd
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04764521

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