Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Indole → 1H-Indole-3-propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Indole | HCID 798 | — |
| 반응물 | Acrylic Acid | HCID 6581 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1H-Indole-3-propanoic acid | HCID 3744 | — |
반응 단계
Reaction of indole XXI with acrylic acid in the presence of acetic acid affords the indole-3-propionic acid. Esterification, alkylation of the indole nitrogen, if desired, and trifluoroacetic acid hydrolysis gives rise to indoles of Formula VII in which R is (CH2)mCO2R9, m is 2 and R2 is H or C1 -C3 alkyl. ##STR29##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04764610 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-67ea4b0a1462429cbc7a0a109d6d2d88 |
| 출처 메모 | uspto-grants-1988_08 |