Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → Methyl 3-(piperidin-1-ylmethyl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Methyl 3-(piperidin-1-ylmethyl)benzoate | HCID 7162043 | — |
반응 단계
A mixture of piperidine (25 ml) and 3-(bromomethyl)benzoic acid, methyl ester (20 g) in toluene (600 ml) was stirred at room temperature for 4 h. The white preciptiate was removed by filtration and the filtrate was distilled to give the title compound as a colourless oil (17.56 g) b.p. 110° (10-1 mm). TLC silica; ether; Rf 0.7.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04764612 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-d2db7d61cdb94d9a851edbff15c6518d |
| 출처 메모 | uspto-grants-1988_08 |