Ethylamine → (1-{9-[(4s,2r,3r,5r)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-n-ethylcarboxamide

HRID 350598

반응식

HRID 350598 반응식
[OH:1][C@@H:2]1[C@H:6]([OH:7])[C@@H:5]([CH2:8][OH:9])[O:4][C@H:3]1[N:10]1[CH:18]=[N:17][C:16]2[C:11]1=[N:12][C:13]([N:20]1[CH:24]=[C:23]([C:25]([NH:27][CH3:28])=[O:26])[CH:22]=[N:21]1)=[N:14][C:15]=2[NH2:19].[CH2:29](N)C>>[OH:1][C@@H:2]1[C@H:6]([OH:7])[C@@H:5]([CH2:8][OH:9])[O:4][C@H:3]1[N:10]1[CH:18]=[N:17][C:16]2[C:11]1=[N:12][C:13]([N:20]1[CH:24]=[C:23]([C:25]([NH:27][CH2:28][CH3:29])=[O:26])[CH:22]=[N:21]1)=[N:14][C:15]=2[NH2:19]

참가 물질

3

반응물 2

HCID 6341EthylamineHCID 219024Regadenoson

생성물 1

HCID 9865924(1-{9-[(4s,2r,3r,5r)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-n-ethylcarboxamide

실험 절차

Compound 19 was prepared in a manner similar to that of compound 16 using ethylamine instead of methylamine, MS 405.35 (M+1).

출처 및 근거

ORD 기록
ord-c5efb11cb3ce4b7e9dc3b1bd472254da
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07183264B2

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