Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Benzyloxy-4-methoxypicolinic acid → 3-Hydroxy-4-methoxypyridine-2-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Benzyloxy-4-methoxypicolinic acid | HCID 19960289 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Hydroxy-4-methoxypyridine-2-carboxylic acid | HCID 11041121 | 81.6% |
반응 단계
3-Benzyloxy-4-methoxypicolinic acid (5.3 g) was suspended in 25 ml of ethanol. 10% palladium-carbon (0.5 g) was added to the suspension. The mixture was then catalytically hydrogenated under atmospheric pressure for 30 min. The reaction solution was filtered under the reduced pressure. The filtrate was concentrated under the reduced pressure to give 2.8 g (yield 81.6%) of the title compound as colorless powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07183278B1 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-fdccc608141d4e1c8f6a5004e9b1d6cb |
| 출처 메모 | uspto-grants-2007_02 |